Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24950299 | 0.87 | CRBN (0.47) | CRBNDDB1 | |
| SCHEMBL26159195 | 0.86 | CRBN (0.40) | CRBNDDB1GAA | |
| SCHEMBL24938771 | 0.85 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL26158808 | 0.83 | DDB1 (0.47) | CRBNDDB1 | |
| SCHEMBL24938746 | 0.81 | CRBN (0.53) | CRBNDDB1 | |
| SCHEMBL23115190 | 0.81 | CRBN (0.52) | CRBNDDB1 | |
| SCHEMBL24938770 | 0.80 | DDB1 (0.44) | CRBNDDB1 | |
| SCHEMBL26158805 | 0.80 | CRBN (0.47) | CRBNDDB1 | |
| SCHEMBL23115188 | 0.79 | CRBN (0.47) | CRBNDDB1 | |
| SCHEMBL30922351 | 0.79 | CRBN (0.47) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | MEDSHINE DISCOVERY INC. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | MEDSHINE DISCOVERY INC. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | PSMA6, PSMC1, PSMA1 | CRBN 111/4885DDB1 2308/4885GAA 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.