Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 8/20 | 0.72 |
| ▸ | KDR | P35968 | 8/20 | 0.72 |
| ▸ | BRAF | P15056 | 2/20 | 0.72 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.72 |
| ▸ | CDK8 | P49336 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | PLK4 | O00444 | 1/20 | 0.72 |
| ▸ | CIT | O14578 | 1/20 | 0.72 |
| ▸ | AURKA | O14965 | 1/20 | 0.72 |
| ▸ | MUSK | O15146 | 1/20 | 0.72 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.72 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.72 |
| ▸ | MLNR | O43193 | 1/20 | 0.72 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.72 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.72 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.72 |
| ▸ | PDE6D | O43924 | 1/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.72 |
| ▸ | STK10 | O94804 | 1/20 | 0.72 |
| ▸ | CDK14 | O94921 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12848167 | 0.88 | RAF1 (0.75) | RAF1KDRBRAFAURKBCDK8 | |
| SCHEMBL29543439 | 0.88 | RAF1 (0.75) | RAF1KDRBRAFAURKBCDK8 | |
| SCHEMBL3711970 | 0.87 | RAF1 (0.77) | RAF1KDRBRAFAURKBCDK8 | |
| SCHEMBL10000735 | 0.87 | RAF1 (0.83) | RAF1KDRBRAFAURKBCDK8 | |
| SCHEMBL26158852 | 0.86 | RAF1 (0.79) | RAF1KDRBRAFAURKBCDK8 | |
| SCHEMBL4344749 | 0.85 | RAF1 (0.78) | RAF1KDRBRAFAURKBCDK8 | |
| SCHEMBL24535359 | 0.85 | RAF1 (0.84) | RAF1KDRBRAFAURKBCDK8 | |
| SCHEMBL3407209 | 0.85 | RAF1 (0.80) | RAF1KDRBRAFAURKBCDK8 | |
| SCHEMBL8465098 | 0.85 | RAF1 (0.75) | RAF1KDRBRAFAURKBCDK8 | |
| SCHEMBL936533 | 0.85 | RAF1 (0.73) | RAF1KDRBRAFAURKBCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | MEDSHINE DISCOVERY INC. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | MEDSHINE DISCOVERY INC. (CN) | 2023-05-25 | — | — | US | disclosed |
| EP-4122925-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | Medshine Discovery Inc. (CN) | 2023-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | PSMA6, PSMC1, PSMA1 | RAF1 1691/4885KDR 3355/4885BRAF 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.