Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.51 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24951258 | 0.84 | PDE10A (0.53) | PDE10APDE4APDE4BSLC6A3 | |
| SCHEMBL29280467 | 0.83 | BRAF (0.44) | PDE10ASLC6A3 | |
| SCHEMBL17088202 | 0.81 | PDE10A (0.57) | PDE10ASLC6A3 | |
| SCHEMBL1758443 | 0.80 | PDE10A (0.70) | PDE10ASLC6A3 | |
| SCHEMBL1758488 | 0.80 | PDE10A (0.52) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL3276042 | 0.80 | PDE10A (0.69) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL1758710 | 0.79 | PDE10A (0.71) | PDE10APDE4APDE4B | |
| SCHEMBL30202117 | 0.79 | PDE10A (0.53) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL1847543 | 0.79 | BRAF (0.39) | PDE10ASLC6A3 | |
| SCHEMBL17088203 | 0.78 | PDE10A (0.51) | PDE10APDE4APDE4BPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4377305-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | disclosed |
| CN-117751107-A | Organic pyridine-pyrazole compounds and uses thereof | 博善人工智能剑桥有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2023007184-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023007184-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |