Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24951243 | 0.85 | BRAF (0.43) | BRAFSLC6A3MEN1KMT2APDE10A | |
| SCHEMBL24950801 | 0.83 | PDE10A (0.51) | SLC6A3PDE10A | |
| SCHEMBL31074565 | 0.80 | MAPK14 (0.34) | BRAFSLC6A3MEN1KMT2APDE10A | |
| SCHEMBL31111573 | 0.80 | DGAT1 (0.37) | BRAFSLC6A3PDE10AMAPK3MAPK1 | |
| SCHEMBL24950777 | 0.79 | BRAF (0.57) | BRAFSLC6A3MEN1KMT2AMAPK3 | |
| SCHEMBL1847543 | 0.79 | BRAF (0.39) | BRAFSLC6A3PDE10AMAPK3MAPK1 | |
| SCHEMBL1847873 | 0.79 | TGFBR1 (0.39) | BRAFSLC6A3PDE10AMAPK14 | |
| SCHEMBL1846834 | 0.78 | BRAF (0.37) | BRAFSLC6A3PDE10AMAPK3MAPK1 | |
| SCHEMBL31111773 | 0.77 | PDE10A (0.37) | PDE10AMAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL1758620 | 0.77 | BRAF (0.46) | BRAFSLC6A3MEN1KMT2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751107-A | Organic pyridine-pyrazole compounds and uses thereof | 博善人工智能剑桥有限公司 | 2024-03-22 | — | — | CN | disclosed |