Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 12/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20558425 | 0.85 | BTK (0.46) | KMT2ABTKPDE2AKDM4EMAPT | |
| SCHEMBL24951116 | 0.85 | KMT2A (0.37) | KMT2ABTKPDE2AKDM4EALDH1A1 | |
| SCHEMBL20558330 | 0.84 | BTK (0.41) | KMT2ABTKPDE2A | |
| SCHEMBL30202779 | 0.84 | KMT2A (0.47) | KMT2ABTKPDE2AKDM4EALDH1A1 | |
| SCHEMBL30202737 | 0.84 | KDM4C (0.39) | KMT2ABTKPDE2AALDH1A1GAA | |
| SCHEMBL30202669 | 0.82 | TP53 (0.37) | KMT2ABTKMAPTGAA | |
| SCHEMBL20558323 | 0.82 | GAA (0.43) | KMT2ABTKPDE2AKDM4EMAPT | |
| SCHEMBL20558422 | 0.81 | BTK (0.55) | KMT2ABTKPDE2AKDM4EALDH1A1 | |
| SCHEMBL24951699 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPT | |
| SCHEMBL30202836 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007009-A1 | PYRAZOLOPYRIMIDINES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-02-02 | — | — | WO | disclosed |