Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24952003 | 1.00 | HRH3 (0.46) | HRH3ALDH1A1HRH2HRH1NPSR1 | |
| SCHEMBL24952278 | 0.94 | — | — | |
| SCHEMBL4390662 | 0.94 | — | — | |
| SCHEMBL4395261 | 0.94 | — | — | |
| SCHEMBL16604390 | 0.80 | HRH3 (0.51) | HRH3ALDH1A1HRH2HRH1NPSR1 | |
| SCHEMBL12873386 | 0.79 | ALDH1A1 (0.42) | HRH3ALDH1A1KDM4ECXCR4 | |
| SCHEMBL21667807 | 0.78 | ALDH1A1 (0.45) | HRH3ALDH1A1KDM4ECXCR4 | |
| SCHEMBL21667806 | 0.78 | ALDH1A1 (0.45) | HRH3ALDH1A1KDM4ECXCR4 | |
| SCHEMBL21743290 | 0.78 | ALDH1A1 (0.45) | HRH3ALDH1A1KDM4ECXCR4 | |
| SCHEMBL21941321 | 0.76 | ALDH1A1 (0.40) | HRH3ALDH1A1KDM4ECHRM2CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007009-A1 | PYRAZOLOPYRIMIDINES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-02-02 | — | — | WO | disclosed |
| CN-104072489-B | Therapeutic isoxazole compounds | 达特神经科学(开曼)有限公司 | 2017-07-07 | — | — | CN | disclosed |