Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498907 | 0.81 | DRD4 (0.34) | DRD4 | |
| SCHEMBL13887674 | 0.79 | HRH3 (0.46) | DRD4HRH3DRD3 | |
| SCHEMBL9801701 | 0.79 | HRH3 (0.46) | DRD4HRH3DRD3 | |
| SCHEMBL26820367 | 0.78 | PDK1 (0.41) | TLR8TLR7 | |
| SCHEMBL24951986 | 0.78 | PDK1 (0.41) | TLR8TLR7 | |
| SCHEMBL25743378 | 0.78 | CACNA1H (0.34) | DRD4 | |
| SCHEMBL25743432 | 0.78 | CACNA1H (0.34) | DRD4 | |
| Bromide SCHEMBL19439574 | 0.77 | HRH3 (0.44) | DRD4HRH3DRD3 | |
| SCHEMBL26510904 | 0.76 | DRD4 (0.35) | DRD4HRH3DRD3 | |
| SCHEMBL25565642 | 0.76 | DRD3 (0.51) | DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007009-A1 | PYRAZOLOPYRIMIDINES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-02-02 | — | — | WO | disclosed |