Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.67 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.67 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.67 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8851713 | 0.96 | GNAI3 (0.61) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL6247785 | 0.89 | GNAI3 (0.73) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL8851875 | 0.87 | GNAI3 (0.55) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL8682833 | 0.84 | GNAI3 (0.67) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL3265058 | 0.83 | GNAI3 (0.92) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL19604164 | 0.82 | GNAI3 (0.96) | GNAI3GNAO1GNAI1KCNH2EPHX1 | |
| SCHEMBL19604163 | 0.82 | GNAI3 (0.96) | GNAI3GNAO1GNAI1KCNH2EPHX1 | |
| SCHEMBL27763474 | 0.82 | GNAI3 (0.96) | GNAI3GNAO1GNAI1KCNH2EPHX1 | |
| SCHEMBL28793539 | 0.82 | GNAI3 (0.96) | GNAI3GNAO1GNAI1KCNH2EPHX1 | |
| SCHEMBL7319928 | 0.82 | GNAI3 (0.96) | GNAI3GNAO1GNAI1KCNH2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4177258-A1 | ARYLPHOSPHINE OXIDE COMPOUNDS AND USE THEREOF | Chengdu Di'Ao Jiuhong Pharmaceutical Factory (CN) | 2023-05-10 | — | — | EP | disclosed |
| EP-3656769-B1 | ARYL-PHOSPHORUS-OXYGEN COMPOUND AS EGFR KINASE INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2023-01-25 | — | — | EP | disclosed |