Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 5/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30202081 | 0.84 | PDE10A (0.36) | PIK3CAPDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL24955777 | 0.84 | PDE10A (0.36) | PIK3CAPDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL30202402 | 0.80 | HTR2C (0.45) | PIK3R1PIK3CAPDE10AKDM4EALDH1A1 | |
| SCHEMBL24954159 | 0.80 | HTR2C (0.45) | PIK3R1PIK3CAPDE10AKDM4EALDH1A1 | |
| SCHEMBL24956799 | 0.79 | MTOR (0.51) | PIK3R1PIK3CAMTOR | |
| SCHEMBL30202052 | 0.79 | MTOR (0.51) | PIK3R1PIK3CAMTOR | |
| SCHEMBL24955640 | 0.72 | PIK3CA (0.47) | PIK3R1PIK3CAPDE10AKDM4EALDH1A1 | |
| SCHEMBL24955834 | 0.71 | MEN1 (0.43) | PIK3CAPDE10AALDH1A1MTOR | |
| SCHEMBL24955831 | 0.71 | SRC (0.39) | PIK3CAPDE10AKDM4EALDH1A1HPGD | |
| SCHEMBL24956795 | 0.71 | PIK3CA (0.48) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4377313-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | claimed |
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | claimed |
| EP-4377313-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | disclosed |
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |