Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 8/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24955833 | 0.90 | PIK3CA (0.46) | PIK3CAPDE10AALDH1A1LRRK2PIK3R1 | |
| SCHEMBL30202390 | 0.86 | PDE10A (0.38) | PIK3CAPDE10ALRRK2ADORA1 | |
| SCHEMBL30203054 | 0.86 | CNR2 (0.38) | PIK3CAPDE10AADORA1 | |
| SCHEMBL24955686 | 0.86 | PDE10A (0.38) | PIK3CAPDE10ALRRK2ADORA1 | |
| SCHEMBL30202248 | 0.86 | MTOR (0.49) | PIK3CAPDE10AMTOR | |
| SCHEMBL30202168 | 0.86 | MTOR (0.49) | PIK3CAPDE10AMTOR | |
| SCHEMBL24955629 | 0.84 | PIK3CA (0.39) | PIK3CANOS1PDE10AKDM4EALDH1A1 | |
| SCHEMBL24955681 | 0.83 | PIK3CA (0.46) | PIK3CANOS1PDE10AKDM4EALDH1A1 | |
| SCHEMBL24955834 | 0.82 | MEN1 (0.43) | PIK3CAPDE10AALDH1A1ADORA1SMN1; SMN2 | |
| SCHEMBL30202224 | 0.81 | PIK3CA (0.37) | PIK3CAPDE10AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |