Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24953102 | 0.83 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL23551580 | 0.81 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL24890785 | 0.81 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL26519222 | 0.80 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL25627114 | 0.80 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL25627115 | 0.80 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL25627113 | 0.80 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL25595387 | 0.80 | DDB1 (0.65) | DDB1CRBN | |
| SCHEMBL25567229 | 0.79 | CRBN (0.57) | DDB1CRBN | |
| SCHEMBL24848348 | 0.77 | DDB1 (0.77) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006063-A1 | PYRROLO [2, 3-b] PYRAZINE-BASED BIFUNCTIONAL COMPOUNDS AS HPK1 DEGRADERS AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2023-02-02 | — | — | WO | disclosed |