SCHEMBL25595387

SCHEMBL25595387

CCc1ccc2ccc(NC3CCC(=O)NC3=O)cc2n1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.65
CRBN Q96SW2 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24890785 0.81 DDB1 (0.59) DDB1CRBN
SCHEMBL23551580 0.81 DDB1 (0.59) DDB1CRBN
SCHEMBL24955737 0.80 DDB1 (0.56) DDB1CRBN
SCHEMBL21965436 0.79 CRBN (1.00) DDB1CRBN
SCHEMBL27275050 0.77 DDB1 (0.57) DDB1CRBN
SCHEMBL24678275 0.76 DDB1 (0.74) DDB1CRBN
SCHEMBL24752789 0.76 CRBN (0.63) DDB1CRBN
SCHEMBL23551581 0.75 DDB1 (0.53) DDB1CRBN
SCHEMBL24848348 0.74 DDB1 (0.77) DDB1CRBN
SCHEMBL25567132 0.73 DDB1 (0.57) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023083194-A1 WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF 杭州格博生物医药有限公司 2023-05-19 WO disclosed