Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.33 |
| ▸ | MTOR | P42345 | 7/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31106977 | 1.00 | CNR2 (0.35) | CNR2ADORA2AADORA1LMNANPSR1 | |
| SCHEMBL24955619 | 0.86 | PIK3CA (0.42) | PIK3CAMTOR | |
| SCHEMBL31106974 | 0.86 | PIK3CA (0.42) | PIK3CAMTOR | |
| SCHEMBL24955665 | 0.83 | ADORA2A (0.35) | CNR2ADORA2AADORA1PIK3CAMTOR | |
| SCHEMBL24954191 | 0.81 | PIK3CA (0.33) | CNR2ADORA2AADORA1PIK3CAMTOR | |
| SCHEMBL31106985 | 0.81 | CNR2 (0.38) | CNR2PIK3CAMTOR | |
| SCHEMBL24955763 | 0.81 | CNR2 (0.38) | CNR2PIK3CAMTOR | |
| SCHEMBL31106958 | 0.79 | PDE2A (0.46) | PIK3CAMTORPKM | |
| SCHEMBL24955621 | 0.79 | PDE2A (0.46) | PIK3CAMTORPKM | |
| SCHEMBL24955626 | 0.76 | PIK3CA (0.42) | CNR2PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |