Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.32 |
| ▸ | MTOR | P42345 | 12/20 | 0.32 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24955660 | 0.87 | MTOR (0.40) | PIK3CAMTOR | |
| SCHEMBL24954191 | 0.86 | PIK3CA (0.33) | ADORA2AADORA1PIK3CAMTORCNR2 | |
| SCHEMBL31106977 | 0.83 | CNR2 (0.35) | ADORA2AADORA1PIK3CAMTORCNR2 | |
| SCHEMBL24955764 | 0.83 | CNR2 (0.35) | ADORA2AADORA1PIK3CAMTORCNR2 | |
| SCHEMBL31106981 | 0.82 | CNR2 (0.36) | PIK3CAMTORCNR2 | |
| SCHEMBL24955674 | 0.82 | CNR2 (0.36) | PIK3CAMTORCNR2 | |
| SCHEMBL31106943 | 0.81 | HRH1 (0.38) | PIK3CAMTOR | |
| SCHEMBL24955655 | 0.81 | HRH1 (0.38) | PIK3CAMTOR | |
| SCHEMBL24955664 | 0.78 | PIK3CA (0.40) | PIK3CAMTOR | |
| SCHEMBL31106993 | 0.78 | PIK3CA (0.40) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343729-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2024-10-17 | — | — | US | disclosed |
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343729-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | SI, SLC10A2, NOS3 | ADORA2A 4021/4885ADORA1 2488/4885PIK3CA 2011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.