Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536614 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2KMT2ANUDT1KDM4EALDH1A1 | |
| SCHEMBL2626729 | 0.80 | KMT2A (0.44) | SMN1; SMN2KMT2ANUDT1KDM4EALDH1A1 | |
| SCHEMBL28896270 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2ANUDT1KDM4EALDH1A1 | |
| SCHEMBL1492325 | 0.79 | KDM4E (0.50) | SMN1; SMN2KMT2ANUDT1KDM4EALDH1A1 | |
| SCHEMBL18557963 | 0.78 | KMT2A (0.43) | SMN1; SMN2KMT2ANUDT1KDM4EALDH1A1 | |
| SCHEMBL4200796 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2KMT2ANUDT1KDM4EALDH1A1 | |
| SCHEMBL25892876 | 0.78 | KMT2A (0.43) | SMN1; SMN2KMT2ANUDT1KDM4EALDH1A1 | |
| SCHEMBL25241521 | 0.78 | KDM4E (0.51) | KMT2ANUDT1KDM4EALDH1A1LMNA | |
| SCHEMBL1536739 | 0.77 | TSHR (0.45) | SMN1; SMN2KMT2ANUDT1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL25312311 | 0.76 | TSHR (0.44) | SMN1; SMN2KMT2ANUDT1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230023543-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230023543-A1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN2C, GRIN2A, GRIN1 | SMN1; SMN2 4683/4885KMT2A 573/4885NUDT1 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.