SCHEMBL24958739

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12817987	0.83	CSNK2A2 (0.39)	PKMNPC1CFTRALDH1A1KDM4E
	SCHEMBL24958740	0.82	DAO (0.41)	PKMNPC1SMARCA2SMARCA4ALDH1A1
	SCHEMBL25183576	0.77	CDK8 (0.37)	SMARCA2SMARCA4ALDH1A1KDM4EGAA
	SCHEMBL28316078	0.77	CSNK2A2 (0.41)	PKMNPC1NOTUMALDH1A1KDM4E
	SCHEMBL1912667	0.74	CA12 (0.41)	PKMNPC1ALDH1A1KDM4EL3MBTL1
	SCHEMBL22367374	0.74	CSNK2A2 (0.42)	NPC1ALDH1A1KDM4EL3MBTL1POLB
	SCHEMBL19274421	0.73	KDM4E (0.38)	NPC1NOTUMALDH1A1KDM4EL3MBTL1
	SCHEMBL28315326	0.73	CFTR (0.38)	PKMNPC1CFTRALDH1A1KDM4E
	SCHEMBL28316585	0.73	KDM4E (0.40)	NPC1NOTUMALDH1A1KDM4EL3MBTL1
	SCHEMBL24525158	0.72	CFTR (0.52)	NOTUMCFTRALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.