Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840651 | 0.82 | IDO1 (0.53) | CYP1A2ALDH1A1IMPDH2IMPDH1HTT | |
| SCHEMBL27730 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HTTTSHRMAPTKDM4E | |
| SCHEMBL49632 | 0.74 | TSHR (0.43) | CYP1A2ALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL637626 | 0.74 | CYP1A2 (0.62) | CYP1A2CYP2A6ALDH1A1IMPDH2IMPDH1 | |
| SCHEMBL29712920 | 0.73 | CYP1A2 (0.68) | CYP1A2CYP2A6ALDH1A1TSHRMAPT | |
| SCHEMBL9824756 | 0.73 | CYP1A2 (0.68) | CYP1A2CYP2A6ALDH1A1TSHRMAPT | |
| SCHEMBL2502170 | 0.73 | NCEH1 (0.53) | CYP1A2CYP2A6ALDH1A1TSHRMAPT | |
| SCHEMBL14950810 | 0.72 | CYP1A2 (0.59) | CYP1A2CYP2A6ALDH1A1IMPDH2IMPDH1 | |
| SCHEMBL97030 | 0.72 | NCEH1 (0.34) | MAPT | |
| SCHEMBL161370 | 0.72 | CYP1A2 (1.00) | CYP1A2CYP2A6ALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431663-B2 | Polymer and method for producing same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2013-04-30 | — | — | US | disclosed |
| US-8389656-B2 | Copolymer and method for producing same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20110245441-A1 | POLYMER AND METHOD FOR PRODUCING SAME | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-10-06 | — | — | US | disclosed |
| US-20110245440-A1 | COPOLYMER AND METHOD FOR PRODUCING SAME | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4859759-A | Siloxane containing benzotriazolyl/tetraalkylpiperidyl substituent | KIMBERLY-CLARK CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |