SCHEMBL249609

SCHEMBL249609

NC(=O)c1ccc(C(=O)n2c3ccc2cc3)c(S(=O)(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 1/20 0.39
CA2 P00918 2/20 0.35
GAA P10253 1/20 0.35
PARP1 P09874 2/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
BRD4 O60885 1/20 0.33
BRPF1 P55201 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LCK P06239 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ACLY P53396 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
CDC25B P30305 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245823 0.88 SMN1; SMN2 (0.35) SMN1; SMN2MAPK1CA2PARP1ALDH1A1
SCHEMBL359496 0.82 CA2 (0.42) SMN1; SMN2MAPK1CA2PARP1LCK
SCHEMBL8204033 0.79 MYC (0.39) SMN1; SMN2MAPK1GAAPARP1HSD17B10
SCHEMBL10684097 0.78 PARP1 (0.42) SMN1; SMN2PARP1ALDH1A1KDM4EBRD4
SCHEMBL9067479 0.76 IP6K1 (0.42) SMN1; SMN2PARP1ALDH1A1KDM4EBRD4
SCHEMBL11875631 0.74 MKNK1 (0.42) CA2BRD4CA12CA1CA9
SCHEMBL1755175 0.72 CDC25B (0.55) SMN1; SMN2MAPK1CA2PARP1ALDH1A1
SCHEMBL8959130 0.72 PARP1 (0.55) SMN1; SMN2GAAPARP1ALDH1A1LMNA
SCHEMBL15088030 0.71 CA2 (0.39) SMN1; SMN2CA2ALDH1A1CA12CA1
SCHEMBL174536 0.70 PARP10 (0.46) SMN1; SMN2CA2GAAPARP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638126-B1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2015-02-18 EP claimed
JP-2012500316-A 2012-01-05 JP claimed
EP-2331655-A2 COMPOSITION OF ORGANIC COMPOUNDS, OPTICAL FILM AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2011-06-15 EP claimed
US-6096453-A Polymeric thin-film reversible electrochemical charge storage devices ADVEN POLYMERS, INC. (US) 2000-08-01 US claimed
US-RE45850-E1 Composition of organic compounds, optical film and method of production thereof CRYSOPTIX K.K. (JP) 2016-01-19 US disclosed
US-9212296-B2 Organic compound, optical film and method of production thereof CRYSOPTIX KK (JP) 2015-12-15 US disclosed
US-20150086799-A1 ORGANIC POLYMER COMPOUNDS SUITABLE FOR FORMING POSITIVE A-TYPE RETARDERS AND METHODS OF PRODUCTION THEREOF LIGHT POLYMERS HOLDING (KY) 2015-03-26 US disclosed
EP-2638126-B1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2015-02-18 EP disclosed
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-20140334002-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2014-11-13 US disclosed
US-20140186637-A1 Organic Compound, Optical Film and Method of Production thereof CRYSOPTIX KK (JP) 2014-07-03 US disclosed
US-8512824-B2 Composition of organic compounds, optical film and method of production thereof CRYSOPTIX KK (JP) 2013-08-20 US disclosed
WO-2013003780-A1 THREE-DIMENSIONAL CIRCULAR POLARIZATION EYEGLASSES CRYSOPTIX KK (JP) 2013-01-03 WO disclosed
EP-2279233-B1 ORGANIC COMPOUND, OPTICAL FILM AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2012-09-05 EP disclosed
US-20120113380-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2012-05-10 US disclosed
US-20120099052-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-04-26 US disclosed
US-20120081784-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 US disclosed
US-20100085521-A1 Composition of Organic Compounds, Optical Film and Method of Production Thereof CRYSOPTIX KK (JP) 2010-04-08 US disclosed
US-20090269591-A1 Organic Compound, Optical Film and Method of Production thereof CRYSOPTIX KK (JP) 2009-10-29 US disclosed
US-6096453-A Polymeric thin-film reversible electrochemical charge storage devices ADVEN POLYMERS, INC. (US) 2000-08-01 US disclosed