Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 7/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 10/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 4/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24961969 | 0.95 | MTOR (0.44) | MTORPIK3CAPIK3CDATRATRIP | |
| SCHEMBL27233200 | 0.95 | MTOR (0.44) | MTORPIK3CAPIK3CDATRATRIP | |
| SCHEMBL30516414 | 0.88 | PIK3CD (0.46) | PIK3CAPIK3CDATRATRIPCHEK1 | |
| SCHEMBL24961679 | 0.81 | MTOR (0.38) | MTORPIK3CAATRATRIPCHEK1 | |
| SCHEMBL24962177 | 0.80 | RAD52 (0.40) | — | |
| SCHEMBL26297233 | 0.79 | RAD52 (0.45) | MTORPIK3CAPIK3CDATRATRIP | |
| SCHEMBL24962028 | 0.79 | DPP4 (0.36) | — | |
| SCHEMBL24962149 | 0.78 | PDE10A (0.46) | MTORPIK3CAPIK3CDATRATRIP | |
| SCHEMBL24962148 | 0.78 | PDE10A (0.46) | MTORPIK3CAPIK3CDATRATRIP | |
| SCHEMBL26297239 | 0.78 | PIK3CD (0.41) | MTORPIK3CAPIK3CDATRATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023005928-A1 | 8-OXO-3-AZABICYCLO[3.2.1]OCTANE COMPOUND OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-02-02 | — | — | WO | disclosed |