Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 10/20 | 0.43 |
| ▸ | MTOR | P42345 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 9/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.39 |
| ▸ | ATRIP | Q8WXE1 | 7/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24962148 | 1.00 | PDE10A (0.46) | PDE10AATRMTORPDE4DPDCD1 | |
| SCHEMBL30516414 | 0.87 | PIK3CD (0.46) | ATRPDE4DPDCD1CD274CHEK1 | |
| SCHEMBL25159980 | 0.81 | ATR (0.49) | PDE10AATRPDE4DPDCD1CD274 | |
| SCHEMBL24961968 | 0.78 | MTOR (0.39) | ATRMTORPDE4DPDCD1CD274 | |
| SCHEMBL24961969 | 0.78 | MTOR (0.44) | ATRMTORPDE4DPDCD1CD274 | |
| SCHEMBL27233200 | 0.78 | MTOR (0.44) | ATRMTORPDE4DPDCD1CD274 | |
| SCHEMBL13263839 | 0.77 | PDE10A (0.54) | PDE10A | |
| SCHEMBL2370376 | 0.77 | MTOR (0.55) | ATRMTORPIK3CA | |
| SCHEMBL2370380 | 0.77 | MTOR (0.55) | ATRMTORPIK3CA | |
| SCHEMBL24170909 | 0.77 | ATR (0.42) | ATRMTORPDCD1CD274CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677730-A | 8-oxygen-3-azabicyclo [3.2.1] octane compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-2023005928-A1 | 8-OXO-3-AZABICYCLO[3.2.1]OCTANE COMPOUND OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-02-02 | — | — | WO | disclosed |