Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 14/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104870 | 0.91 | NPBWR1 (0.46) | NPBWR1MCHR1BRD4 | |
| SCHEMBL24687640 | 0.89 | NPBWR1 (0.51) | NPBWR1MCHR1MAPK1PKMPKLR | |
| SCHEMBL24962321 | 0.88 | NPBWR1 (0.48) | NPBWR1MCHR1MAPK1L3MBTL1PKM | |
| SCHEMBL24687647 | 0.87 | NPBWR1 (0.49) | NPBWR1MCHR1PKMPKLRBRD4 | |
| SCHEMBL21521227 | 0.87 | NPBWR1 (0.51) | NPBWR1MCHR1MAPK1PKMPKLR | |
| SCHEMBL21521225 | 0.87 | NPBWR1 (0.51) | NPBWR1MCHR1MAPK1PKMPKLR | |
| SCHEMBL24640479 | 0.87 | NPBWR1 (0.51) | NPBWR1MCHR1MAPK1PKMPKLR | |
| SCHEMBL24687786 | 0.84 | NPBWR1 (0.46) | NPBWR1MCHR1MAPK1PKMPKLR | |
| SCHEMBL24962319 | 0.84 | NPBWR1 (0.44) | NPBWR1MCHR1MAPK1PKM | |
| SCHEMBL24467751 | 0.83 | NPBWR1 (0.46) | NPBWR1MCHR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001247-A1 | PYRIDAZINONE COMPOUND | 南京明德新药研发有限公司 | 2023-01-26 | — | — | WO | disclosed |