Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25238346 | 0.80 | HDAC1 (0.36) | HDAC1HDAC6SIGMAR1KCNH2 | |
| SCHEMBL19945613 | 0.80 | HDAC1 (0.36) | HDAC1HDAC6SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL25186761 | 0.78 | HDAC1 (0.35) | HDAC1HDAC6SIGMAR1KCNH2 | |
| SCHEMBL21471170 | 0.77 | HDAC1 (0.34) | HDAC1HDAC6SIGMAR1KCNH2 | |
| SCHEMBL24958729 | 0.76 | HDAC1 (0.41) | HDAC1HDAC6SIGMAR1KCNH2PDE4D | |
| SCHEMBL21471126 | 0.76 | HDAC1 (0.34) | HDAC1HDAC6SIGMAR1KCNH2 | |
| SCHEMBL23794528 | 0.76 | HDAC1 (0.34) | HDAC1HDAC6SIGMAR1KCNH2 | |
| SCHEMBL16260512 | 0.76 | HDAC1 (0.36) | HDAC1HDAC6SIGMAR1KCNH2 | |
| SCHEMBL31389771 | 0.74 | SIGMAR1 (0.38) | HDAC1HDAC6SIGMAR1KCNH2NOTUM | |
| SCHEMBL21462809 | 0.74 | POLB (0.35) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001061-A1 | CDK7 SELECTIVE INHIBITORS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |