SCHEMBL24965008

SCHEMBL24965008

C=CP(=O)(OCCCCCCCCCCOP(=O)(C=C)OCC(C)C)OCC(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.38
LPAR2 Q9HBW0 6/20 0.38
LPAR1 Q92633 4/20 0.33
TSHR P16473 1/20 0.33
CDC25A P30304 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23497214 1.00 LPAR3 (0.38) LPAR3LPAR2LPAR1TSHRCDC25A
SCHEMBL23497248 1.00 LPAR3 (0.38) LPAR3LPAR2LPAR1TSHRCDC25A
SCHEMBL8383286 0.88 TSHR (0.40) TSHR
SCHEMBL23518533 0.87 LPAR2 (0.30) LPAR3LPAR2
SCHEMBL23518664 0.87 LPAR2 (0.30) LPAR3LPAR2
SCHEMBL20377389 0.85 LPAR3 (0.38) LPAR3LPAR2LPAR1CDC25A
SCHEMBL31519188 0.83 LPAR3 (0.35) LPAR3LPAR2LPAR1
SCHEMBL11310369 0.79 TSHR (0.34) TSHR
SCHEMBL24966318 0.79 LPAR3 (0.55) LPAR3LPAR2LPAR1TSHRCDC25A
SCHEMBL24966575 0.79 LPAR3 (0.55) LPAR3LPAR2LPAR1TSHRCDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540148-B2 Lipophosphonoxins, their preparation and use USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2026-02-03 US disclosed
EP-4072681-B1 LIPOPHOSPHONOXINS, THEIR PREPARATION AND USE USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2025-03-12 EP disclosed
US-20230028523-A1 LIPOPHOSPHONOXINS, THEIR PREPARATION AND USE USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2023-01-26 US disclosed
US-20230028523-A1 LIPOPHOSPHONOXINS, THEIR PREPARATION AND USE USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230028523-A1 LIPOPHOSPHONOXINS, THEIR PREPARATION AND USE PHOSPHO1, PLA2G10, PLA2G1B LPAR3 44/4885LPAR2 47/4885LPAR1 24/4885
US-12540148-B2 Lipophosphonoxins, their preparation and use PLD1, LYPLA1, LPAR3 LPAR3 3/4885LPAR2 25/4885LPAR1 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.