SCHEMBL2496543

SCHEMBL2496543

O=C(O)Cc1ccc2cccc(O)c2n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.57
KMT2A Q03164 3/20 0.57
PIM1 P11309 1/20 0.51
METAP2 P50579 2/20 0.49
PLAU P00749 1/20 0.49
NCF1 P14598 1/20 0.49
ALDH1A1 P00352 3/20 0.47
ALOX12 P18054 3/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HIF1A Q16665 1/20 0.47
LMNA P02545 2/20 0.45
MAPT P10636 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
SOS2 Q07890 1/20 0.45
POLB P06746 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31568905 1.00 KDM4E (0.57) KDM4EKMT2APIM1METAP2PLAU
SCHEMBL28239913 0.84 KMT2A (0.51) KDM4EKMT2APIM1METAP2PLAU
SCHEMBL12047119 0.83 KDM4E (0.54) KDM4EKMT2APIM1METAP2PLAU
SCHEMBL14610935 0.83 CCR1 (0.54) KDM4EPIM1ALDH1A1HPGDHSD17B10
SCHEMBL27847384 0.81 BACE1 (0.47) KDM4EKMT2AALDH1A1HPGDHSD17B10
SCHEMBL7050557 0.81 KDM4E (0.47) KDM4EKMT2APIM1METAP2PLAU
SCHEMBL7371340 0.81 KDM4E (0.47) KDM4EKMT2APIM1METAP2PLAU
SCHEMBL7562315 0.80 KMT2A (0.50) KDM4EKMT2APIM1METAP2PLAU
SCHEMBL4394002 0.80 METAP2 (0.57) KDM4EKMT2APIM1METAP2PLAU
SCHEMBL3212638 0.80 METAP2 (0.57) KDM4EKMT2APIM1METAP2PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103003383-B Can by the binding property polyurethane powder of heat-activated A. RAYMOND ET CIE. (FR) 2015-10-14 CN claimed
CN-1282735-A Amphiphili 8-hydroxyquinoline complex, its preparing process and its application in electroluminescence UNIV JINAN (CN) 2001-02-07 CN claimed
EP-0299045-A1 NEW TYPES OF COLD BIOPROBES COMPRISING A CLUSTER OF ALCYNE-CARBONYLE METAL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-01-18 EP claimed
WO-1988005439-A1 NEW TYPES OF COLD BIOPROBES COMPRISING A CLUSTER OF ALCYNE-CARBONYLE METAL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 1988-07-28 WO claimed
WO-2023162868-A1 COMPOSITION 富士フイルム株式会社 2023-08-31 WO disclosed
CN-108440527-A A kind of acidification corrosion inhibitor and the preparation method and application thereof based on mutual aggressiveness indole derivative 中国石油大学(华东) 2018-08-24 CN disclosed
CN-103228752-B System and method for producing heat-activatable adhesive particles A. RAYMOND ET CIE. (FR) 2015-10-14 CN disclosed
CN-103228752-A System and method for producing heat-activatable adhesive particles ARAYMOND S A 2013-07-31 CN disclosed
CN-102149783-B Methods and compositions for polishing silicon-containing substrates CABOT MICROELECTRONICS CORP 2013-06-12 CN disclosed
US-8030458-B2 Monoclonal antibodies to tacrolimus and immunoassays methods for tacrolimus SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2011-10-04 US disclosed
CN-102149783-A Methods and compositions for polishing silicon-containing substrates CABOT MICROELECTRONICS CORP 2011-08-10 CN disclosed
CN-101959865-A Quinolines as farnesyl pyrophosphate synthase inhibitor NOVARTIS AG 2011-01-26 CN disclosed
CN-1282735-A Amphiphili 8-hydroxyquinoline complex, its preparing process and its application in electroluminescence UNIV JINAN (CN) 2001-02-07 CN disclosed
EP-0675358-A1 Monitoring water treatment agent in-system concentration and regulating dosage NALCO CHEMICAL COMPANY (US) 1995-10-04 EP disclosed
EP-0415442-B1 Method for detecting an analyte BOEHRINGER MANNHEIM GMBH (DE) 1994-09-07 EP disclosed
US-5312763-A Method for the detection of analytes BOEHRINGER MANNHEIM GMBH (DE) 1994-05-17 US disclosed
EP-0415442-A2 Method for detecting an analyte Roche Diagnostics GmbH (DE) 1991-03-06 EP disclosed
EP-0299045-A1 NEW TYPES OF COLD BIOPROBES COMPRISING A CLUSTER OF ALCYNE-CARBONYLE METAL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-01-18 EP disclosed
WO-1988005439-A1 NEW TYPES OF COLD BIOPROBES COMPRISING A CLUSTER OF ALCYNE-CARBONYLE METAL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 1988-07-28 WO disclosed
EP-0193889-B1 PROCESS FOR REGENERATING INACTIVE AND POISENED PLATINUM CATALYSTS BASF Aktiengesellschaft (DE) 1988-04-27 EP disclosed