Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.49 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16151569 | 1.00 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNA7CHRNA5CHRNB4 | |
| SCHEMBL24967966 | 0.95 | CHRNB2 (0.44) | CHRNB2CHRNA4CHRNA7CHRNA5 | |
| SCHEMBL13929717 | 0.86 | CHRNB2 (0.52) | CHRNB2CHRNA4CHRNA7CHRNA5CHRNB4 | |
| SCHEMBL24967967 | 0.83 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA7CHRNA5CHRNB4 | |
| SCHEMBL13695531 | 0.81 | CHRNB2 (0.48) | CHRNB2CHRNA4CHRNA7CHRNA5 | |
| SCHEMBL2459458 | 0.81 | CHRNB4 (0.50) | CHRNB4CHRNA3 | |
| SCHEMBL13929716 | 0.81 | CHRNB2 (0.48) | CHRNB2CHRNA4CHRNA7CHRNA5 | |
| SCHEMBL26724258 | 0.79 | CHRM3 (0.44) | CHRNB2CHRNA4CHRNA7CHRNA5 | |
| SCHEMBL24578244 | 0.79 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7CHRNA5 | |
| SCHEMBL20869642 | 0.79 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |