⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14779495 | 0.81 | — | — | |
| SCHEMBL1018739 | 0.74 | — | — | |
| SCHEMBL18020383 | 0.74 | — | — | |
| SCHEMBL14778897 | 0.73 | — | — | |
| SCHEMBL14778776 | 0.73 | — | — | |
| SCHEMBL12997262 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL11814475 | 0.71 | — | — | |
| SCHEMBL7226727 | 0.70 | — | — | |
| SCHEMBL8611287 | 0.69 | — | — | |
| SCHEMBL14777966 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022157-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT FACTOR D MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-01-26 | — | — | US | disclosed |