Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30851325 | 1.00 | PIK3CD (0.35) | PIK3CDPIK3CAPIK3CBSSTR4HTR2B | |
| SCHEMBL27233804 | 0.84 | AR (0.45) | PIK3CDPIK3CAPIK3CBAURKAKDR | |
| SCHEMBL27233739 | 0.84 | AR (0.45) | PIK3CDPIK3CAPIK3CBAURKAKDR | |
| SCHEMBL27233810 | 0.84 | AR (0.45) | PIK3CDPIK3CAPIK3CBAURKAKDR | |
| SCHEMBL24968932 | 0.84 | AR (0.45) | PIK3CDPIK3CAPIK3CBAURKAKDR | |
| SCHEMBL24968340 | 0.84 | AR (0.45) | PIK3CDPIK3CAPIK3CBAURKAKDR | |
| SCHEMBL24968337 | 0.84 | AR (0.45) | PIK3CDPIK3CAPIK3CBAURKAKDR | |
| SCHEMBL24968215 | 0.82 | FFAR1 (0.35) | PIK3CDPIK3CAPIK3CBSSTR4RIPK1 | |
| SCHEMBL24968213 | 0.79 | SLC6A2 (0.44) | PIK3CDPIK3CAPIK3CBSSTR4HTR2B | |
| SCHEMBL24968383 | 0.78 | TACR1 (0.35) | PIK3CDPIK3CAPIK3CBSSTR4HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4378938-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2024-06-05 | — | — | EP | disclosed |
| CN-117642393-A | Novel PARP7 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |