Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968932 | 1.00 | AR (0.45) | ARPIK3CDPIK3CAAURKAKDR | |
| SCHEMBL27233739 | 1.00 | AR (0.45) | ARPIK3CDPIK3CAAURKAKDR | |
| SCHEMBL27233810 | 1.00 | AR (0.45) | ARPIK3CDPIK3CAAURKAKDR | |
| SCHEMBL24968340 | 1.00 | AR (0.45) | ARPIK3CDPIK3CAAURKAKDR | |
| SCHEMBL27233804 | 1.00 | AR (0.45) | ARPIK3CDPIK3CAAURKAKDR | |
| SCHEMBL24968217 | 0.84 | PIK3CD (0.35) | PIK3CDPIK3CAAURKAKDRAURKB | |
| SCHEMBL30851325 | 0.84 | PIK3CD (0.35) | PIK3CDPIK3CAAURKAKDRAURKB | |
| SCHEMBL24968213 | 0.82 | SLC6A2 (0.44) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24968383 | 0.78 | TACR1 (0.35) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24968934 | 0.77 | PIK3CD (0.35) | PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |