Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30851258 | 1.00 | AURKA (0.37) | AURKAKDRAURKBCFTRMAPT | |
| SCHEMBL27233748 | 0.88 | AURKA (0.37) | AURKAKDRAURKBCFTRMAPT | |
| SCHEMBL21031170 | 0.82 | AURKA (0.40) | AURKAKDRAURKBCFTRMAPT | |
| SCHEMBL30776172 | 0.81 | AURKA (0.39) | AURKAKDRAURKBCFTRMAPT | |
| SCHEMBL27233788 | 0.81 | AURKA (0.39) | AURKAKDRAURKBCFTRMAPT | |
| SCHEMBL29208803 | 0.81 | AURKA (0.39) | AURKAKDRAURKBCFTRMAPT | |
| SCHEMBL932942 | 0.81 | AURKA (0.39) | AURKAKDRAURKBCFTRMAPT | |
| SCHEMBL30851110 | 0.79 | LMNA (0.39) | AURKAKDRAURKBCFTRMAPT | |
| SCHEMBL24967935 | 0.79 | SMN1; SMN2 (0.47) | LMNACYP11B1CYP11B2 | |
| SCHEMBL30851253 | 0.79 | SMN1; SMN2 (0.47) | LMNACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642393-A | Novel PARP7 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |