Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24967960 | 0.90 | MEN1 (0.49) | KMT2AMEN1SMN1; SMN2HPGDTIPARP | |
| SCHEMBL24968351 | 0.90 | MEN1 (0.54) | KMT2AMEN1SMN1; SMN2HPGDTIPARP | |
| SCHEMBL27233858 | 0.88 | MEN1 (0.46) | KMT2AMEN1SMN1; SMN2HPGDTIPARP | |
| SCHEMBL24968229 | 0.87 | TIPARP (0.52) | KMT2AMEN1SMN1; SMN2HPGDTIPARP | |
| SCHEMBL24968396 | 0.84 | CHRM4 (0.44) | KMT2AMEN1SMN1; SMN2TIPARPALDH1A1 | |
| SCHEMBL24968471 | 0.84 | SMN1; SMN2 (0.60) | KMT2AMEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL24967947 | 0.82 | TIPARP (0.46) | KMT2AMEN1SMN1; SMN2HPGDTIPARP | |
| SCHEMBL24967941 | 0.80 | TIPARP (0.43) | KMT2AMEN1SMN1; SMN2HPGDTIPARP | |
| SCHEMBL24967958 | 0.80 | HPGD (0.42) | KMT2AMEN1SMN1; SMN2HPGDTIPARP | |
| SCHEMBL24967955 | 0.79 | TIPARP (0.42) | KMT2AMEN1SMN1; SMN2HPGDTIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |