SCHEMBL24967941 — predicted protein targets

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	TIPARP	Q7Z3E1	11/20	0.43

▸	MAPT	P10636	4/20	0.42

▸	HPGD	P15428	3/20	0.42

▸	MEN1	O00255	3/20	0.42

▸	KMT2A	Q03164	3/20	0.42

▸	ALDH1A1	P00352	2/20	0.42

▸	SMN1; SMN2	Q16637	3/20	0.40

▸	NPSR1	Q6W5P4	3/20	0.37

▸	KDM4E	B2RXH2	1/20	0.37

▸	TSHR	P16473	2/20	0.37

▸	HSD17B10	Q99714	2/20	0.37

▸	HTT	P42858	2/20	0.37

▸	CYP1A2	P05177	2/20	0.37

▸	CYP2C9	P11712	2/20	0.37

▸	CYP2C19	P33261	2/20	0.37

▸	CYP2D6	P10635	1/20	0.37

▸	ALOX15	P16050	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24968229	0.92	TIPARP (0.52)	TIPARPHPGDMEN1KMT2ASMN1; SMN2
SCHEMBL24967947	0.90	TIPARP (0.46)	TIPARPMAPTHPGDMEN1KMT2A
SCHEMBL24967955	0.89	TIPARP (0.42)	TIPARPMAPTHPGDMEN1KMT2A
SCHEMBL24968854	0.88	TIPARP (0.42)	TIPARPMAPTHPGDMEN1KMT2A
SCHEMBL24968853	0.87	TIPARP (0.41)	TIPARPMAPTHPGDMEN1KMT2A
SCHEMBL24968235	0.85	WDR5 (0.37)	TIPARP
SCHEMBL24968357	0.85	GPR119 (0.37)	TIPARP
SCHEMBL24968347	0.85	WDR5 (0.37)	TIPARP
SCHEMBL24968349	0.85	WDR5 (0.37)	TIPARP
SCHEMBL24968351	0.85	MEN1 (0.54)	TIPARPMAPTHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023006013-A1	NOVEL PARP7 INHIBITOR AND USE THEREOF	上海齐鲁制药研究中心有限公司	2023-02-02	—	—	WO	disclosed