Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.46 |
| ▸ | CA2 | P00918 | 14/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2496817 | 1.00 | CA1 (0.46) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2835696 | 0.85 | CA2 (0.45) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL2835690 | 0.85 | CA2 (0.45) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL2835689 | 0.85 | CA2 (0.45) | CA1CA2CA12CA9HSD17B10 | |
| SCHEMBL10292503 | 0.84 | CA2 (0.47) | CA1CA2FOLH1 | |
| SCHEMBL17997541 | 0.82 | FOLH1 (0.52) | FOLH1 | |
| SCHEMBL15512642 | 0.82 | FOLH1 (0.52) | FOLH1 | |
| SCHEMBL2794828 | 0.82 | FOLH1 (0.52) | FOLH1 | |
| SCHEMBL23553141 | 0.82 | FOLH1 (0.47) | FOLH1 | |
| SCHEMBL22984221 | 0.82 | FOLH1 (0.47) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373621-A2 | TECHNETIUM-AND RHENIUM-BIS(HETEROARYL)COMPLEXES AND METHODS OF USE THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010065899-A2 | TECHNETIUM-AND RHENIUM-BIS(HETEROARYL)COMPLEXES AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |