Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 8/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968933 | 0.82 | PIK3CD (0.34) | PIK3R1PIK3CACFTR | |
| SCHEMBL24968341 | 0.82 | PIK3CD (0.34) | PIK3R1PIK3CACFTR | |
| SCHEMBL27233855 | 0.81 | PIK3CD (0.35) | TACR1PIK3CACFTR | |
| SCHEMBL24968338 | 0.81 | PIK3CD (0.35) | TACR1PIK3CACFTR | |
| SCHEMBL24968934 | 0.81 | PIK3CD (0.35) | TACR1PIK3CACFTR | |
| SCHEMBL27233713 | 0.81 | TIPARP (0.47) | TIPARP | |
| SCHEMBL24968936 | 0.81 | TIPARP (0.47) | TIPARP | |
| SCHEMBL24968387 | 0.76 | TIPARP (0.47) | TIPARP | |
| SCHEMBL24968383 | 0.75 | TACR1 (0.35) | TACR1PIK3CACFTR | |
| SCHEMBL24968385 | 0.72 | CYP11B1 (0.36) | TACR1PIK3CAPTK2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |