Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27233855 | 1.00 | PIK3CD (0.35) | PIK3CDPIK3CATACR1RIPK1KCNK3 | |
| SCHEMBL24968338 | 1.00 | PIK3CD (0.35) | PIK3CDPIK3CATACR1RIPK1KCNK3 | |
| SCHEMBL24968933 | 0.91 | PIK3CD (0.34) | PIK3CDPIK3CARIPK1KCNK3PIK3CB | |
| SCHEMBL24968341 | 0.91 | PIK3CD (0.34) | PIK3CDPIK3CARIPK1KCNK3PIK3CB | |
| SCHEMBL24968383 | 0.90 | TACR1 (0.35) | PIK3CDPIK3CATACR1RIPK1KCNK3 | |
| SCHEMBL24968385 | 0.82 | CYP11B1 (0.36) | PIK3CDPIK3CATACR1RIPK1KCNK3 | |
| SCHEMBL24968936 | 0.81 | TIPARP (0.47) | — | |
| SCHEMBL27233713 | 0.81 | TIPARP (0.47) | — | |
| SCHEMBL24968337 | 0.77 | AR (0.45) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL24968932 | 0.77 | AR (0.45) | PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |