Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 16/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30851256 | 1.00 | MRGPRX4 (0.59) | MRGPRX4NR4A2NR1H2NR1H3RXRA | |
| SCHEMBL24968420 | 0.89 | MRGPRX4 (0.53) | MRGPRX4NR1H2NR1H3 | |
| SCHEMBL27233839 | 0.81 | RXRA (0.48) | MRGPRX4NR1H2NR1H3RXRARXRB | |
| SCHEMBL30165056 | 0.80 | TIPARP (0.62) | MRGPRX4 | |
| SCHEMBL24968427 | 0.80 | TIPARP (0.62) | MRGPRX4 | |
| SCHEMBL29165923 | 0.77 | MRGPRX4 (0.35) | MRGPRX4NR1H2NR1H3RXRARXRB | |
| SCHEMBL27233846 | 0.75 | MRGPRX4 (0.45) | MRGPRX4NR4A2NR1H2NR1H3RXRA | |
| SCHEMBL29165959 | 0.75 | MRGPRX4 (0.40) | MRGPRX4NR1H2NR1H3RXRARXRB | |
| SCHEMBL22480756 | 0.74 | MRGPRX4 (1.00) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL31568457 | 0.74 | MRGPRX4 (1.00) | MRGPRX4NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642393-A | Novel PARP7 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |