Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13596286 | 0.91 | MAPT (0.39) | MAPTKDM1APOLBCA1CA2 | |
| Hydrochloric Acid SCHEMBL30225271 | 0.89 | MAPT (0.38) | MAPTKDM1APOLBCA1CA2 | |
| SCHEMBL12556801 | 0.84 | MAPT (0.38) | MAPTKDM1APOLBCA1CA2 | |
| SCHEMBL25748793 | 0.83 | MAPT (0.35) | MAPTKDM1APOLBHDAC2SMN1; SMN2 | |
| SCHEMBL25760253 | 0.83 | MAPT (0.35) | MAPTKDM1APOLBHDAC2SMN1; SMN2 | |
| SCHEMBL21850085 | 0.78 | CA1 (0.34) | CA1CA2RECQL | |
| SCHEMBL25869574 | 0.78 | MAPT (0.36) | MAPTKDM1APOLBHDAC2SMN1; SMN2 | |
| SCHEMBL25748770 | 0.78 | MAPT (0.36) | MAPTKDM1APOLBHDAC2SMN1; SMN2 | |
| SCHEMBL2757943 | 0.77 | CACNA1H (0.42) | MAPTKDM1APOLBHDAC2SMN1; SMN2 | |
| SCHEMBL22064537 | 0.77 | CA1 (0.38) | CA1CA2ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007481-A1 | WATER SOLUBLE PRODRUG, CONJUGATES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-02-02 | — | — | WO | disclosed |