SCHEMBL24968705

SCHEMBL24968705

Clc1cccc2sc3cccc(-c4ccccc4)c3c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.52
MCL1 Q07820 2/20 0.45
MAPK1 P28482 1/20 0.45
LIMK1 P53667 2/20 0.44
OGG1 O15527 1/20 0.37
F9 P00740 1/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
MAOB P27338 2/20 0.36
PLK4 O00444 1/20 0.36
MAPK9 P45984 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
AKT3 Q9Y243 1/20 0.36
MAPK14 Q16539 1/20 0.36
CYP1A2 P05177 2/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
HSD11B1 P28845 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25567689 0.82 CYP2A6 (0.42) CYP2A6MCL1MAPK1LIMK1OGG1
SCHEMBL25569776 0.82 LIMK1 (0.46) CYP2A6MCL1MAPK1LIMK1F9
SCHEMBL31568860 0.82 MAPK1 (0.53) CYP2A6MCL1MAPK1OGG1MEN1
SCHEMBL24627946 0.82 APP (0.44) MCL1MAPK1MEN1ALDH1A1KMT2A
SCHEMBL25567635 0.82 ALOX5 (0.46) CYP2A6MCL1MAPK1LIMK1OGG1
SCHEMBL23765004 0.81 MAPK1 (0.41) CYP2A6MCL1MAPK1LIMK1OGG1
SCHEMBL24969647 0.81 LIMK1 (0.48) CYP2A6MCL1MAPK1LIMK1F9
SCHEMBL22019102 0.81 CYP2A6 (0.47) CYP2A6MCL1MAPK1LIMK1OGG1
SCHEMBL24627986 0.80 ABL1 (0.43) CYP2A6MAPK1LIMK1MEN1ALDH1A1
SCHEMBL24627987 0.79 ABL1 (0.39) CYP2A6MCL1MAPK1LIMK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023003234-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-01-26 WO disclosed