Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 2/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026714 | 0.95 | GAA (0.47) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL5616695 | 0.88 | GAA (0.42) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL19286436 | 0.87 | GAA (0.41) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL1024018 | 0.82 | GAA (0.42) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL21198529 | 0.82 | GAA (0.47) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL24610343 | 0.82 | GAA (0.47) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL29659128 | 0.82 | GAA (0.47) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL2144073 | 0.82 | GAA (0.47) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL1025883 | 0.81 | GAA (0.38) | GAACYP4F2CYP4A11RETALDH1A1 | |
| SCHEMBL18281904 | 0.80 | GAA (0.41) | GAACYP4F2CYP4A11RETALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230021916-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA LIMITED (GB) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230021916-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | ROCK2, ROCK1, RHOA | GAA 2236/4885CYP4F2 3606/4885CYP4A11 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.