Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968321 | 0.94 | GPR119 (0.40) | GPR119KCNH2TIPARP | |
| SCHEMBL24968911 | 0.94 | GPR119 (0.40) | GPR119KCNH2TIPARP | |
| SCHEMBL24968944 | 0.94 | GPR119 (0.40) | GPR119KCNH2TIPARP | |
| SCHEMBL24968505 | 0.92 | GPR119 (0.39) | GPR119KCNH2MMP2MMP14ADAMTS5 | |
| SCHEMBL24968906 | 0.88 | GPR119 (0.37) | GPR119TIPARPWDR5 | |
| SCHEMBL24968926 | 0.88 | GPR119 (0.37) | GPR119TIPARPWDR5 | |
| SCHEMBL24968909 | 0.88 | GPR119 (0.37) | GPR119TIPARPWDR5 | |
| SCHEMBL24968245 | 0.88 | GPR119 (0.37) | GPR119TIPARPWDR5 | |
| SCHEMBL24968304 | 0.87 | TIPARP (0.42) | TIPARP | |
| SCHEMBL24968907 | 0.87 | TIPARP (0.42) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |