Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.56 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152362 | 1.00 | EGFR (0.56) | EGFRERBB2ERBB4MRGPRX4PTGDR2 | |
| SCHEMBL24969075 | 0.95 | EGFR (0.53) | EGFRERBB2ERBB4MRGPRX4PTGDR2 | |
| SCHEMBL24969094 | 0.85 | EGFR (0.61) | EGFRERBB2ERBB4LRRK2JAK3 | |
| SCHEMBL24968809 | 0.83 | EGFR (0.75) | EGFRERBB2ERBB4 | |
| SCHEMBL24968811 | 0.83 | EGFR (0.59) | EGFRERBB2ERBB4MRGPRX4MAOB | |
| SCHEMBL24969077 | 0.82 | EGFR (0.58) | EGFRERBB2ERBB4 | |
| SCHEMBL24969076 | 0.81 | EGFR (0.57) | EGFRERBB2ERBB4MRGPRX4MAOB | |
| SCHEMBL24968448 | 0.80 | EGFR (0.56) | EGFRERBB2ERBB4MRGPRX4 | |
| SCHEMBL30152371 | 0.80 | EGFR (0.56) | EGFRERBB2ERBB4MRGPRX4 | |
| SCHEMBL24969078 | 0.80 | MAOB (0.55) | EGFRMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |