Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.52 |
| ▸ | ITK | Q08881 | 8/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 2/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969092 | 0.94 | EGFR (0.51) | EGFRITKEPHX2TGM2BRAF | |
| SCHEMBL28456327 | 0.84 | EGFR (0.69) | EGFRITKTGM2KDR | |
| SCHEMBL24969095 | 0.79 | EGFR (0.50) | EGFRITKTGM2BRD4 | |
| SCHEMBL24968812 | 0.78 | EGFR (0.54) | EGFRITKTGM2 | |
| SCHEMBL24969097 | 0.77 | EGFR (0.49) | EGFRITKTGM2BRAFKDR | |
| SCHEMBL24969100 | 0.77 | EGFR (0.47) | EGFRITKTGM2 | |
| SCHEMBL24969151 | 0.76 | S1PR1 (0.52) | EGFRITKTGM2BRAFKDR | |
| SCHEMBL24968859 | 0.76 | EGFR (0.51) | EGFRITKTGM2KDR | |
| SCHEMBL24969094 | 0.75 | EGFR (0.61) | EGFRITKTGM2 | |
| SCHEMBL24969098 | 0.75 | TGM2 (0.51) | EGFRITKTGM2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |