Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.50 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.48 |
| ▸ | ITK | Q08881 | 8/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 3/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152295 | 1.00 | EGFR (0.50) | EGFRERBB2ERBB4SGMS2ITK | |
| SCHEMBL24969094 | 0.82 | EGFR (0.61) | EGFRERBB2ERBB4SGMS2ITK | |
| SCHEMBL30152279 | 0.81 | SYK (0.47) | SGMS2BTKLRRK2 | |
| SCHEMBL24968494 | 0.80 | NR4A2 (0.59) | EGFRERBB2ERBB4TGM2 | |
| SCHEMBL24969129 | 0.78 | EGFR (0.54) | EGFRERBB2ERBB4SGMS2JAK3 | |
| SCHEMBL15968627 | 0.76 | LRRK2 (0.48) | SGMS2LRRK2 | |
| SCHEMBL24968809 | 0.76 | EGFR (0.75) | EGFRERBB2ERBB4 | |
| SCHEMBL24968811 | 0.76 | EGFR (0.59) | EGFRERBB2ERBB4JAK3BTK | |
| SCHEMBL24968496 | 0.75 | MAOB (0.57) | EGFR | |
| SCHEMBL24969077 | 0.75 | EGFR (0.58) | EGFRERBB2ERBB4ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |