Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | PTGIR | P43119 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497708 | 0.91 | PTGDR2 (0.56) | PTGDR2TBXA2RPTGDRALDH1A1HPGD | |
| SCHEMBL12197402 | 0.89 | ALDH1A1 (0.52) | ALDH1A1HPGDCYP2C9NPC1RAB9A | |
| SCHEMBL2505141 | 0.84 | PTGDR2 (0.56) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2501971 | 0.82 | PTGDR2 (0.54) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2502491 | 0.82 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2502525 | 0.81 | PTGDR2 (0.58) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2500305 | 0.80 | PTGDR2 (0.57) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL150599 | 0.80 | PTGDR2 (0.57) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2496068 | 0.80 | PTGDR2 (0.58) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL12197405 | 0.79 | ALDH1A1 (0.54) | PTGDR2ALDH1A1HPGDCYP2C9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524748-B2 | Heteroalkyl biphenyl antagonists of prostaglandin D2 receptors | PANMIRA PHARMACEUTICALS, LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524748-B2 | Heteroalkyl biphenyl antagonists of prostaglandin D2 receptors | PANMIRA PHARMACEUTICALS, LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-20110245303-A1 | HETEROALKYL BIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-20110245303-A1 | HETEROALKYL BIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2010042652-A2 | HETEROALKYL BIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010042652-A2 | HETEROALKYL BIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245303-A1 | HETEROALKYL BIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | PTGDR, PTGDR2, PTGER2 | PTGDR2 2/4885TBXA2R 6/4885PTGDR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.