Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31296544 | 0.85 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1DYRK1AMAPT | |
| SCHEMBL1545257 | 0.85 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1DYRK1AMAPT | |
| SCHEMBL13075575 | 0.82 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1DYRK1AMAPT | |
| SCHEMBL31620610 | 0.81 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1DYRK1APOLB | |
| SCHEMBL10270980 | 0.81 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1DYRK1APOLB | |
| SCHEMBL17007009 | 0.79 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1AMAPT | |
| SCHEMBL165125 | 0.79 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1AALDH1A1 | |
| SCHEMBL796465 | 0.79 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1ALMNA | |
| SCHEMBL13466852 | 0.79 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1AMAPT | |
| SCHEMBL991921 | 0.79 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |