SCHEMBL24969561 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	TGM2	P21980	12/20	0.61

▸	F13A1	P00488	2/20	0.51

▸	TGM1	P22735	2/20	0.51

▸	LMNA	P02545	1/20	0.51

▸	TGM3	Q08188	1/20	0.51

▸	EGFR	P00533	5/20	0.44

▸	ITK	Q08881	2/20	0.44

▸	GSTO1	P78417	1/20	0.43

▸	ERBB2	P04626	2/20	0.43

▸	BTK	Q06187	1/20	0.43

▸	MMP1	P03956	1/20	0.43

▸	MMP2	P08253	1/20	0.43

▸	MMP9	P14780	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30152202	1.00	TGM2 (0.61)	TGM2F13A1TGM1LMNATGM3
SCHEMBL20500840	0.86	TGM2 (0.61)	TGM2F13A1TGM1LMNATGM3
SCHEMBL29767497	0.86	TGM2 (0.61)	TGM2F13A1TGM1LMNATGM3
SCHEMBL7621031	0.86	TGM2 (0.65)	TGM2F13A1TGM1LMNATGM3
SCHEMBL28295696	0.84	TGM2 (0.56)	TGM2F13A1TGM1LMNATGM3
SCHEMBL25297445	0.81	TGM2 (0.59)	TGM2F13A1TGM1LMNATGM3
SCHEMBL31596193	0.81	TGM2 (0.59)	TGM2F13A1TGM1LMNATGM3
SCHEMBL25223736	0.80	TGM2 (0.57)	TGM2F13A1TGM1LMNATGM3
SCHEMBL28546969	0.79	TGM2 (0.61)	TGM2F13A1TGM1LMNATGM3
SCHEMBL24968501	0.79	TGM2 (0.59)	TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023009785-A1	TEAD INHIBITORS AND USES THEREOF	CEDILLA THERAPEUTICS, INC. (US)	2023-02-02	—	—	WO	disclosed