Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 13/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30903378 | 1.00 | MEN1 (0.47) | MEN1KMT2ANR1H2NR1H3P2RY12 | |
| SCHEMBL2419414 | 0.90 | MEN1 (0.52) | MEN1KMT2ANR1H2NR1H3P2RY12 | |
| SCHEMBL2418785 | 0.85 | MEN1 (0.52) | MEN1KMT2ANR1H2NR1H3P2RY12 | |
| SCHEMBL31050093 | 0.85 | MEN1 (0.52) | MEN1KMT2ANR1H2NR1H3P2RY12 | |
| SCHEMBL2417915 | 0.85 | MEN1 (0.52) | MEN1KMT2ANR1H2NR1H3P2RY12 | |
| SCHEMBL2419355 | 0.84 | P2RY12 (0.62) | MEN1KMT2AP2RY12 | |
| SCHEMBL2419418 | 0.83 | CXCR3 (0.51) | MEN1KMT2ANR1H2NR1H3P2RY12 | |
| SCHEMBL23064366 | 0.83 | NR1H2 (0.58) | MEN1KMT2ANR1H2NR1H3P2RY12 | |
| SCHEMBL3171182 | 0.82 | MEN1 (0.53) | MEN1KMT2ANR1H2NR1H3LMNA | |
| SCHEMBL30903367 | 0.82 | MEN1 (0.53) | MEN1KMT2ANR1H2NR1H3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373808-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | Institut national de la santé et de la recherche médicale (INSERM) (FR) | 2024-05-29 | — | — | EP | disclosed |
| CN-118076585-A | Gram negative bacteria efflux pump inhibitors | 国家医疗保健研究所 | 2024-05-24 | — | — | CN | disclosed |
| WO-2023002011-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-01-26 | — | — | WO | disclosed |
| WO-2023002011-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-01-26 | — | — | WO | disclosed |