Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31142967 | 1.00 | KIT (0.46) | KITP2RY12NR1H2NR1H3SLC2A1 | |
| SCHEMBL31142973 | 0.87 | P2RY12 (0.46) | KITP2RY12NR1H2NR1H3MEN1 | |
| SCHEMBL24969726 | 0.86 | P2RY12 (0.46) | KITP2RY12NR1H2NR1H3MEN1 | |
| SCHEMBL31143040 | 0.83 | MEN1 (0.44) | KITP2RY12NR1H2NR1H3MEN1 | |
| SCHEMBL31143082 | 0.82 | MEN1 (0.46) | KITNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL31143001 | 0.82 | MEN1 (0.43) | KITNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL19212401 | 0.76 | P2RY12 (0.54) | KITP2RY12SLC2A1MEN1KMT2A | |
| SCHEMBL31142861 | 0.75 | MEN1 (0.47) | KITNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL31142932 | 0.75 | NR1H2 (0.43) | KITP2RY12NR1H2NR1H3MEN1 | |
| SCHEMBL24969739 | 0.74 | SMN1; SMN2 (0.48) | P2RY12MEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002011-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-01-26 | — | — | WO | disclosed |