Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
| ▸ | MGLL | Q99685 | 3/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | IL1B | P01584 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920387 | 1.00 | FAAH (0.51) | FAAHMGLLNR1H2JAK1JAK2 | |
| SCHEMBL30218721 | 1.00 | FAAH (0.51) | FAAHMGLLNR1H2JAK1JAK2 | |
| SCHEMBL24970046 | 1.00 | FAAH (0.51) | FAAHMGLLNR1H2JAK1JAK2 | |
| SCHEMBL25640092 | 0.87 | FAAH (0.57) | FAAHMGLLNR1H2JAK1JAK2 | |
| SCHEMBL20567053 | 0.87 | FAAH (0.57) | FAAHMGLLNR1H2JAK1JAK2 | |
| SCHEMBL25640104 | 0.87 | FAAH (0.57) | FAAHMGLLNR1H2JAK1JAK2 | |
| SCHEMBL20567052 | 0.87 | FAAH (0.57) | FAAHMGLLNR1H2JAK1JAK2 | |
| SCHEMBL24970468 | 0.87 | FAAH (0.57) | FAAHMGLLNR1H2JAK1JAK2 | |
| SCHEMBL20920366 | 0.87 | FAAH (0.57) | FAAHMGLLNR1H2JAK1JAK2 | |
| SCHEMBL20567650 | 0.86 | FAAH (0.55) | FAAHMGLLP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630744-B1 | PYRAZOLE MAGL INHIBITORS | H LUNDBECK AS (DK) | 2023-01-25 | — | — | EP | disclosed |