Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.65 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | USP2 | O75604 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25643054 | 0.90 | FAAH (0.79) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL30421125 | 0.88 | FAAH (0.82) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL20566944 | 0.88 | FAAH (0.82) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL24970088 | 0.87 | FAAH (0.67) | FAAHMGLL | |
| SCHEMBL25829957 | 0.80 | FAAH (0.65) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL25829945 | 0.80 | FAAH (0.85) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL23015509 | 0.79 | FAAH (0.57) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL20567303 | 0.79 | FAAH (0.78) | FAAHMGLL | |
| SCHEMBL25830083 | 0.79 | FAAH (0.61) | FAAHMGLL | |
| SCHEMBL25487965 | 0.79 | FAAH (0.72) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630744-B1 | PYRAZOLE MAGL INHIBITORS | H LUNDBECK AS (DK) | 2023-01-25 | — | — | EP | disclosed |