SCHEMBL24970517

SCHEMBL24970517

O=C(N1CCC2(CCCN2Cc2cc(N3CCCC3)cc(C(F)(F)F)c2)CC1)n1ccc(C(O)O)n1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.69
FAAH O00519 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25844248 0.94 MGLL (0.79) MGLLFAAH
SCHEMBL20920503 0.88 MGLL (0.58) MGLLFAAH
SCHEMBL20920403 0.88 MGLL (0.88) MGLLFAAH
SCHEMBL20503652 0.85 MGLL (0.68) MGLLFAAH
SCHEMBL22350723 0.84 MGLL (0.68) MGLLFAAH
SCHEMBL20503477 0.84 MGLL (0.68) MGLLFAAH
SCHEMBL21271167 0.83 MGLL (0.67) MGLLFAAH
SCHEMBL20567170 0.82 MGLL (1.00) MGLLFAAH
SCHEMBL30420474 0.82 MGLL (1.00) MGLLFAAH
SCHEMBL22350724 0.79 MGLL (0.64) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630744-B1 PYRAZOLE MAGL INHIBITORS H LUNDBECK AS (DK) 2023-01-25 EP disclosed